Desquamative Inflammatory Vaginitis (DIV) is a less common cause of vaginal discharge but can be a disabling condition especially when symptoms are severe. It is characterised by a yellow discharge, painful sex, and none of the usual infections are identified. It can mimic atrophic vaginitis in post-menopausal women.
The cause is not fully known but it is thought that there is an immune link.
Diagnosis can be difficult as some doctors are not familiar with the condition and many clinics do not routinely look for it. The vagina is inflamed and the top layers of the vaginal lining are lost. A number of tests including biopsy are done to confirm the diagnosis.
Treatment is empiric but includes antibiotics, steroid and oestrogen creams.